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MTHFR Mutation and Pediatric Dental Risks

Epigenetics is the newest revolution in science; and MTHFR is the center of much talk. Mutation of the gene that creates the Methylene Tetrahydrofolate Reductase [MTHFR] enzyme can cause many health problems including tooth decay and dental erosion due to gastrointestinal reflux. At the same time, children with this mutation are at a heightened risk of a serious and life threatening reaction to some dental anesthesia. Pediatric dental and medical practitioners and parents must be aware of the potential for Nitrous Oxide to deactivate the B12 in infants and toddlers with MTHFR deficiency, and in some cases has led to death. Being aware is the first step in protecting children. The research is growing in the field of epigenetics, and research is connecting these genetic polymorphisms or mutations with health conditions and symptoms with an unknown or mysterious cause. Dr. Darleen Claire Wodzenski continues to work hard to identify pathways to provide support and healing for children at risk, and has made great strides on creating protocols for identifying and responding to challenges related to autoimmunity, epigenetic anomalies, and inflammatory processes. Click on the link below to download a white paper explaining the connection between the MTHFR polymorphism with dental health and dental anesthesia risks. And contact Orchard Human Services or PNE Institute to explore how epigenetics, MAST Cell Activation Disorder, and autoimmune inflammatory processes may be contributing to your child's learning problems, behavior challenges, and even Autism Spectrum Disorder diagnosis. Click here to download the FREE white paper on MTHFR and Pediatric Medical and Dental Practice

Concerned about epigenetic phenomenon, global inflammation, or autoimmunity in connection to your child’s development, learning, behavior, Autism, or neurodevelopment? Dr. Darleen Claire sees clients around the metro Atlanta area including Alpharetta, College Park, Cumberland, Marietta, and Hiram. She can be reached at 770-686-0894 or at

Click on this link to learn more about Orchard Human Services, Inc.

Darleen Claire Wodzenski, MS ESE, MA CMHC, PhD Psychology of Orchard Human Services, Inc. and PNE Institute, LLC.